2. Signaling Pathways
  3. Anti-infection
  4. Endoplasmic Reticulum Oxidoreductase 1 (ERO1)

Endoplasmic Reticulum Oxidoreductase 1 (ERO1)

Endoplasmic Reticulum Oxidoreductase 1

Endoplasmic Reticulum Oxidoreductase 1 (ERO1) is a downstream component of the unfolded protein response (UPR) transcriptional regulation and leads to O2 consumption and H2O2 production. ERO1 is essential for maintaining cellular redox balance and adaptability, and ERO1 dysregulation can lead to adverse UPR responses and cell damage.

Endoplasmic Reticulum Oxidoreductase 1 (ERO1) Related Products (5):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-12837
    EN460
    		Inhibitor 99.73%
    EN460 is a selective endoplasmic reticulum oxidation 1 (ERO1) inhibitor. EN460 (IC50 of 1.9 μM) interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation.
    EN460
  • HY-14852
    Tafamidis
    		Inhibitor 99.89%
    Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis.
    Tafamidis
  • HY-B1153
    Glafenine
    		98.75%
    Glafenine (Glafenin) is a non-selective, non-steroidal anti-inflammatory drug-based COX-1/COX-2 inhibitor. Glafenine exerts anti-inflammatory, anti-proliferative and anti-cell migration effects by inhibiting the arachidonic acid metabolic pathway and reducing prostaglandin synthesis. Glafenine can induce cell cycle arrest in vascular smooth muscle cells and endothelial cells and reduce the synthesis of the extracellular matrix protein Tenascin. Glafenine can be used in the research of inflammatory-related diseases, vascular restenosis and cystic fibrosis (CF).
    Glafenine
  • HY-B1153A
    Glafenine hydrochloride
    		99.03%
    Glafenine (Glafenin) hydrochloride is a non-selective, non-steroidal anti-inflammatory drug-based COX-1/COX-2 inhibitor. Glafenine hydrochloride exerts anti-inflammatory, anti-proliferative and anti-cell migration effects by inhibiting the arachidonic acid metabolic pathway and reducing prostaglandin synthesis. Glafenine hydrochloride can induce cell cycle arrest in vascular smooth muscle cells and endothelial cells and reduce the synthesis of the extracellular matrix protein Tenascin. Glafenine hydrochloride can be used in the research of inflammatory-related diseases, vascular restenosis and cystic fibrosis (CF).
    Glafenine hydrochloride
  • HY-148520
    QM295
    		Inhibitor 99.32%
    QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress.
    QM295